Syphilis Singapore | Shim Clinic

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Syphilis in Singapore: Syphilis is caused by Treponema pallidum





Syphilis is a systemic infection caused by Treponema pallidum. With the exception of mother- to-child transmission, syphilis is almost exclusively spread by direct contact with infectious lesions.



  1. (2008). UK National Guidelines on Management of Syphilis. Retrieved from,
  2. Libois, A., De, W.S., Poll, B., Garcia, F., Florance, F., Del Rio, A., et al. (2007). HIV and Syphilis: When to Perform a Lumbar Puncture. Sex Transm Dis, 34:141–4. Retrieved from PubMed.
  3. Rolfs, R.T., Joesoef, M.R., Hendershotm, E.F., Rompalo, A.M., Chiu, M., Bolan, G., et. al. (1997). A Randomised Trial of Eenhanced Therapy for Early Syphilis in Patients With and Without Human Immunodeficiency Virus Infection. N Engl J Med, 337: 307-14. Retrieved from PubMed.
  4. Workowski, K. & Berman, S. (2010). CDC Sexually Transmitted Disease Treatment Guidelines (2010). Retrieved from
  5. Yang, C.J., Chang, S.Y., & Hung, C.C.(2009). Sensitivity and Specificity of Lumbar Puncture in HIV-infected Patients with Syphilis and No Neurologic Symptoms Reply. Clin Infect Dis, 49:162–3. Retrieved from, PubMed.


Syphilis treatment is available!

Sexual risk (of HIV/STD/pregnancy), and what you can do before and after exposure.

Timeline HIV STD Pregnancy
Before exposure
Abstain from sex, Be faithful, or Condom use
Circumcision (males only)
(females only)
HIV PrEP (pre-exposure prophylaxis)
– Stop HIV infection before exposure
STD vaccine:
Hepatitis vaccine
HPV vaccine
STD / HIV exposure
Unsafe sex / unprotected sex:
No condom / Condom broke / Condom slip
0-72 hours HIV PEP (post-exposure prophylaxis)
– Stop HIV infection after exposure
STD testing *
Screening test
– to look for asymptomatic infections
– from previous exposures
Emergency contraception
with the
morning-after pill
(females only)
2 weeks HIV DNA Test
1 month HIV 4th Generation Test
SD Bioline HIV Ag/Ab Combo
– Fingerprick blood sampling.
20 minutes to results
3 months HIV 3rd Generation Test
OraQuick® HIV-1/2 Antibody
– Oral fluid or
– Fingerprick blood sampling.
20 minutes to results
STD testing *
– Full & comprehensive
diagnostic test
– to look for current infections
Watch for HIV Symptoms STD Symptoms
If infected HIV Treatment STD Treatment Abortion

* Males: Do not urinate for at least 4 hours before arriving.
* Females: testing is more accurate when you are not menstruating.


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