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Genital Herpes Testing Singapore | Shim Clinic

Genital Herpes Testing Singapore. As genital herpes is caused by the herpes simplex virus, please refer to herpes simplex testing

 


 

LABORATORY INVESTIGATIONS

Viral isolation in cell culture

This is considered the ‘Gold standard’. The test is both sensitive and specific, but sensitivity declines as lesions heal; viral typing is possible.

Type-specific serological tests (TSSTs)

Based on recombinant type-specific glycoproteins gG1 (HSV-1) and gG2 (HSV-2). Good sensitivity and specificity and are useful in certain clinical situations e.g. confirming a diagnosis of genital herpes, counselling of sexual partners of infected persons, detection of unrecognised infection and for seroepidemiological studies. TSSTs are also useful in high risk populations such as MSM, individuals with multiple sex partners and HIV positive individuals. Screening for HSV-1 and HSV-2 in the general population is not indicated. Examples of these tests are HerpeSelect 1 and 2 ELISA (Focus Technologies, USA) and Immunoblot test kits.

As nearly all HSV-2 infections are sexually acquired, the presence of type-specific HSV-2 antibody implies anogenital infection. Most persons with HSV-1 antibodies have oral HSV infection acquired during childhood, which might be asymptomatic. The presence of HSV-1 antibody does not distinguish anogenital from orolabial infection.

HSV antigen detection

By Direct Immunoflouresence techniques. Results may be available in 1 to 2 days. HSV type is reported if the test is positive.

PCR detection of viral nucleic acid

Highest sensitivity viral typing possible; but expensive and not widely available. Test of choice for detecting HSV in spinal fluid.

Serology

Many commercial tests for HSV antibodies are not type specific and are of NO value in the management of genital herpes.



Sexual risk (of HIV/STD/pregnancy), and what you can do before and after exposure.

Timeline HIV STD Pregnancy
Before exposure
Abstain from sex, Be faithful, or Condom use
Circumcision (males only)
Contraception
(females only)
HIV PrEP (pre-exposure prophylaxis)
– Stop HIV infection before exposure
STD vaccine:
Hepatitis vaccine
HPV vaccine
STD / HIV exposure
Unsafe sex / unprotected sex:
No condom / Condom broke / Condom slip
0-72 hours HIV PEP (post-exposure prophylaxis)
– Stop HIV infection after exposure
STD testing *
Screening test
– to look for asymptomatic infections
– from previous exposures
Emergency contraception
with the
morning-after pill
(females only)
2 weeks HIV DNA Test
1 month HIV 4th Generation Test
SD Bioline HIV Ag/Ab Combo
– Fingerprick blood sampling.
20 minutes to results
3 months HIV 3rd Generation Test
OraQuick® HIV-1/2 Antibody
– Oral fluid or
– Fingerprick blood sampling.
20 minutes to results
STD testing *
– Full & comprehensive
diagnostic test
– to look for current infections
Watch for HIV Symptoms STD Symptoms
If infected HIV Treatment STD Treatment Abortion

* Males: Do not urinate for at least 4 hours before arriving.
* Females: testing is more accurate when you are not menstruating.