Hepatitis B Testing Singapore | Shim Clinic
| Help me about Hepatitis B Testing ! |
Hepatitis B Testing in Singapore: There are a variety of tests for Hepatitis B.
| Abbreviation | Name | Presence in blood indicates |
|---|---|---|
| HBsAg | Hepatitis B Surface Antigen (Australia antigen) |
Carrier |
| HBsAb | Hepatitis B Surface Antibody | Immunity |
| HBeAg | Hepatitis B Envelope Antigen | Infectivity/Activity |
| HBeAb | Hepatitis B Envelope Antibody | Favourable prognosis |
| HBcAg | Hepatitis B Core Antigen | Not detectable in blood Detectable in liver biopsy |
| HBcAb | Hepatitis B Core Antibody | HBsAb presence due to infection |
Blood testing is available for all the above except HBcAg
LABORATORY TESTS
Serologic markers
The order of appearance of markers in acute infections is – HBsAg, HBeAg, antiHBc IgM, antiHBe, antiHBc IgG, antiHBs (Annex VI).
The significance of HBs antigen and antibody markers is shown below:
Marker Clinical Significance
| HBsAg | Presence of HBV |
| HBeAg | Virus replication, High infectivity |
| Anti-HBc IgM | Acute infection |
| Anti-HBc IgG | Late acute or chronic infection |
| Anti-HBe | Loss of replication, low infectivity |
| Anti-HBs | Protective antibody |
Sexual risk (of HIV/STD/pregnancy), and what you can do before and after exposure.
| Timeline | HIV | STD | Pregnancy |
|---|---|---|---|
| Before exposure | |||
| Contraception (females only) |
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| HIV PrEP (pre-exposure prophylaxis) – Stop HIV infection before exposure |
STD vaccine: – Hepatitis vaccine – HPV vaccine |
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| STD / HIV exposure | No condom / Condom broke / Condom slip |
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| 0-72 hours | HIV PEP (post-exposure prophylaxis) – Stop HIV infection after exposure |
STD testing * – Screening test – to look for asymptomatic infections – from previous exposures |
Emergency contraception with the morning-after pill (females only) |
| 2 weeks | HIV DNA Test | ||
| 1 month | HIV 4th Generation Test – SD Bioline HIV Ag/Ab Combo – Fingerprick blood sampling. – 20 minutes to results |
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| 3 months | HIV 3rd Generation Test – OraQuick® HIV-1/2 Antibody – Oral fluid or – Fingerprick blood sampling. – 20 minutes to results |
STD testing * – Full & comprehensive – diagnostic test – to look for current infections |
|
| Watch for | HIV Symptoms | STD Symptoms | |
| If infected | HIV Treatment | STD Treatment | Abortion |
* Males: Do not urinate for at least 4 hours before arriving.
* Females: testing is more accurate when you are not menstruating.
References