Hypogonadism Singapore | Shim Clinic

Help me about Hypogonadism !
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Hypogonadism / late-onset hypogonadism (LOH) screening/diagnosis, testing/check, treatment clinic, Singapore. Private and confidential service. Definitions, references, and latest news.


  • Male hypogonadism
  • Female hypogonadism

Male hypogonadism is a clinical syndrome caused by androgen deficiency. Causes:

  1. Primary hypogonadism, or hypergonadotropic hypogonadism (high LH and/or FSH), or primary testicular failure. Eg: Klinefelters syndrome, Cryptorchidism
  2. Secondary hypogonadism, or hypogonadotropic hypogonadism (low LH and/or FSH), due to a defect in the hypothalamus or the pituitary.
  3. Late onset hypogonadism (LOH)
  4. Male hypogonadism due to androgen receptor insensitivity

Late-onset hypogonadism (LOH) is defined as hypogonadism in a person who has had normal pubertal development and as a result developed normal male secondary sex characteristics.



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