Genital Herpes | Shim Clinic, STD CLINIC SINGAPORE™

Genital Herpes | Shim Clinic, STD CLINIC SINGAPORE™: Genital herpes, cold sores, oral herpes, herpes simplex - symptoms in men/women, screening/diagnosis, testing/check, treatment clinic, Singapore. Private and confidential service. Definitions, references, and latest news.

Description

Contents

• Herpes
• Herpes simplex
• Genital herpes

The signs of herpes appear about 2-10 days after sexual contact with an infected person.

These include:

• itching/burning-feeling in the genital area
• water blisters (vesicles) or open sores
• discharge of fluid from the vagina.

Herpes simplex is caused by the Herpes simplex virus 1 & 2 (HSV-1 & HSV-2), diagnosed with the herpes type-specific blood test and is usually treated with Aciclovir/Acyclovir

Herpes

Human Herpesvirus (HHV) classification

Type & Synonym	Disease	Test	Treatment & prevention
HHV-1 Herpes simplex virus-1 (HSV-1)	Herpes simplex: oral herpes (mainly) commonly called cold sores, genital herpes, herpetic_whitlow, herpes gladiatorum	HS1 IgG	Aciclovir/Acyclovir Valacyclovir
HHV-2 Herpes simplex virus-2 (HSV-2)	Herpes simplex: genital herpes (mainly) oral herpes, herpetic_whitlow	HS2 IgG	Aciclovir/Acyclovir Valacyclovir
HHV-3 Varicella zoster virus (VZV)	Chickenpox & herpes zoster commonly called shingles	VZ IgG	Aciclovir/Acyclovir Valacyclovir Chickenpox vaccine
HHV-4 Epstein-Barr virus (EBV)	Infectious mononucleosis, glandular fever (UK), kissing disease (US), Burkitt's lymphoma, & nasopharyngeal carcinoma	EBV EA-IgA Monospot	Valacyclovir
HHV-5 Cytomegalovirus (CMV)	CMV retinitis, CMV mononucleosis	CMV Ig-M CMV Ig-G	Ganciclovir Foscarnet
HHV-6 Roseolovirus	Sixth disease ( roseola infantum or exanthem subitum)
HHV-7 Roseolovirus	Sixth disease ( roseola infantum or exanthem subitum)
HHV-8 Kaposi's sarcoma- associated herpesvirus (KSHV)	Kaposi's sarcoma

TORCH

References

• Genital herpes - Wikipedia, the free encyclopedia
• Genital herpes: Definition from Answers.com
• Genital herpes - definition of Genital herpes in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia.
• WHO | Herpes virus type 2
• Genital Herpes - STD information from CDC

Refusal of shingles vaccine: Implications for public health
Wed, 16 May 2012 08:07:35 +0100 | Journal of the American Academy of Dermatology
To the Editor: While the varicella-zoster virus (VZV; chickenpox) vaccine (Varivax) is widely utilized and has produced a dramatic decline in VZV-related morbidity and mortality, the herpes zoster virus (HZV) (shingles) vaccine (Zostavax) is used in only 2% to 7% of the target population over 50 years of age in the United States. Research has shown that the HZV vaccine is effective. A randomized, double-blind, placebo-controlled trial involving 38,546 patients 60 years of age or older demonstrated a reduction of 51.3% (P < .001) in the incidence of HZ. Furthermore, those who did develop HZ after receiving the vaccine benefited from a 66.5% (P < .001) decrease in the incidence of postherpetic neuralgia (PHN). Cost-effectiveness is more difficult to prove. Our society generally finds it acce...

In vitro and in vivo evaluation of a novel antiherpetic flavonoid, 4′-phenylflavone, and its synergistic actions with acyclovir
Sat, 12 May 2012 06:16:13 +0100 | Archives of Virology
Abstract  The development of therapeutic agents for preventing herpes simplex virus (HSV) infections has become urgently necessary because of the increasing incidence of this virus and its role as a cofactor in the transmission of human immunodeficiency virus infection. We have evaluated the antiviral activities of a series of natural and synthetic flavonoids and found that a synthetic flavonoid, 4′-phenylflavone, showed the highest activity against acyclovir (ACV)-sensitive and ACV-resistant strains of HSV-1, as well as HSV-2, with a selectivity index of 213, 35 and 55, respectively. Although the attachment and penetration of HSV-1 to host cells and the synthesis of viral proteins were not inhibited, the infectivity of the virus and the amount of progeny virus released w...

HIV and sexually transmitted infections at the borderlands: situational analysis of sexual health in the Brazilian Amazon
Sat, 12 May 2012 04:00:00 +0100 | Sexually Transmitted Infections
Conclusions While the main conditions that contribute to the spread of HIV are in place in the triple-border area, the prevalence of bacterial STIs and HIV are still relatively low, providing a window of opportunity for interventions. (Source: Sexually Transmitted Infections)

FDA Approves Foscarnet for HIV-Related CMV Retinitis, Herpes FDA Approves Foscarnet for HIV-Related CMV Retinitis, Herpes
Fri, 11 May 2012 20:18:13 +0100 | Medscape Hiv----- Headlines
The US Food and Drug Administration has approved foscarnet sodium injection in HIV/-----related cytomegalovirus infections and herpes. FDA Approvals (Source: Medscape Hiv----- Headlines)

Herpes zoster of the penis: an immunohistochemistry diagnosis
Fri, 11 May 2012 04:00:00 +0100 | Journal of Cutaneous Pathology
(Source: Journal of Cutaneous Pathology)

Epidemiological characteristics and societal burden of varicella zoster virus in the Netherlands
Thu, 10 May 2012 04:00:00 +0100 | BMC Infectious Diseases
Conclusions: For varicella the highest incidence of GP-consultations was found in 1-4 year-olds, for herpes zoster in the >65 years olds. The occurrence of complications was not age-dependent but varies per complication. When estimating incidence of VZV-related diseases in primary care, based on diagnostic codes only, one should be aware of a gross underestimation of the incidence. Our analysis may have important implications for the outcomes of upcoming cost-effectiveness analyses on VZV vaccination. (Source: BMC Infectious Diseases)

Biological basis for the protective effect conferred by male circumcision against HIV infection
Thu, 10 May 2012 04:00:00 +0100 | International Journal of STD and ----
Here we provide an up-to-date review of research that explains why uncircumcised men are at higher risk of HIV infection. The inner foreskin is a mucosal epithelium deficient in protective keratin, yet rich in HIV target cells. Soon after sexual exposure to infected mucosal secretions of a HIV-positive partner, infected T-cells from the latter form viral synapses with keratinocytes and transfer HIV to Langerhans cells via dendrites that extend to just under the surface of the inner foreskin. The Langerhans cells with internalized HIV migrate to the basal epidermis and then pass HIV on to T-cells, thus leading to the systemic infection that ensues. Infection is exacerbated in inflammatory states associated with balanoposthitis, the presence of smegma and ulceration – including that ca...

Many cancers caused by 'treatable infections'
Wed, 09 May 2012 16:30:00 +0100 | NHS News Feed
Conclusion This important study highlights the potential role played by certain infections in causing cancer. It uses the highest quality available evidence to calculate the proportion of cancer caused by infectious agents, worldwide and by region. However, as the authors point out, their calculations may be imprecise. For example, many countries have very sparse data on cancer incidence and the prevalence of risk factors for specific cancers. To obtain global estimates researchers had to extrapolate data from other areas. They also say they had to make certain assumptions, for example, that the risk of infection was constant across populations and sexes. They also point out that there was a lack of high quality data from some of the research sites in the studies. In the UK, a vaccine agai...

An Acute Case of Herpes Zoster Ophthalmicus with Ophthalmoplegia
Wed, 09 May 2012 14:16:02 +0100 | Computational Intelligence and Neuroscience
Herpes zoster ophthalmicus (HZO) with oculomotor nerve involvement is rare, even rarer as an acute presentation rather than sequelae of HZO. In this paper we present a case of cutaneous HZO in which our patient's initial presentation was one of complete ophthalmoplegia. (Source: Computational Intelligence and Neuroscience)

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