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Meningococcal Vaccine Singapore.

Meningococcal Vaccine Singapore: Meningococcal vaccine jab/shot/injection schedule, to vaccinate against the Neisseria meningitidis / meningococcus, to immunise against meningococcal disease / meningitis / meningococcemia clinic, Singapore. Private and confidential service. Definitions, references, and latest news.

Polysaccharide and conjugated meningococcal vaccines

Internationally marketed meningococcal polysaccharide vaccines are bivalent (A and C), trivalent (A, C and W-135) or tetravalent (A, C, Y and W-135). The vaccines are purified, heat-stable, lyophilized capsular polysaccharides from meningococci of the respective serogroups.

Both group A and group C vaccines have documented short-term efficacy levels of 85–100% in older children and adults. However, group C vaccines do not prevent disease in children under 2 years of age, and the efficacy of group A vaccine in children under 1 year of age is unclear. Group Y and W-135 polysaccharides have been shown to be immunogenic only in children over 2 years of age.

A protective antibody response occurs within 10 days of vaccination. In schoolchildren and adults, the bivalent and tetravalent polysaccharide vaccines appear to provide protection for at least 3 years, but in children under 4 years the levels of specific antibodies decline rapidly after 2–3 years.

The currently available bivalent and tetravalent meningococcal vaccines are recommended for immunization of specific risk groups as well as for large-scale immunization, as appropriate, for the control of meningococcal outbreaks caused by vaccine-preventable serogroups (A and C, or A, C, Y, W-135 respectively). Travellers who have access to the tetravalent polysaccharide vaccine (A, C, Y, W-135) should opt for this rather than the bivalent vaccine because of the additional protection against groups Y and W-135.

These vaccines do not provide any protection against other serogroups such as group B and group X meningococci, which are important causes of meningococcal disease in some countries.

Precautions and contraindications — polysaccharide vaccine

The internationally available polysaccharide vaccines are safe, and significant systemic reactions have been extremely rare. The most common adverse reactions are erythema and slight pain at the site of injection for 1–2 days. Fever exceeding 38.5 °C occurs in up to 2% of vaccinees. No significant change in safety or reactogenicity has been observed when the different group-specific polysaccharides are combined into bivalent or tetravalent meningococcal vaccines.

Type of vaccine:
1) Purified bacterial capsular polysaccharide meningococcal vaccine (bivalent, trivalent or tetravalent)
2) Conjugate vaccines against A, C, Y, and W135
3) Conjugate MenA vaccine

Number of doses: One

Duration of protection: For 1 and 2: 3–5 years or more; for 3: not known

Contraindications: Serious adverse reaction to previous dose

Adverse reactions: Occasional mild local reactions; rarely, fever

Before departure: 2 weeks

Consider for: 1 and 2: all travellers to countries in the sub-Saharan meningitis belt and to areas with current epidemics; Hajj and Umrah pilgrims (required); 3: a cheaper alterative to 1 and 2 for travellers to highly endemic African countries

Special precautions: Children under 2 years of age are not protected by the vaccine

Conjugate meningococcal vaccines

A T-cell-dependent immune response is achieved through conjugation of the polysaccharide to a protein carrier. Conjugate vaccines are therefore associated with an increased immunogenicity among infants and prolonged duration of protection.

Monovalent serogroup C conjugate vaccines were first licensed for use in 1999 and are now incorporated in national vaccination programmes in an increasing number of countries. In contrast to group C polysaccharide vaccines, the group C conjugate vaccine elicits adequate antibody responses and immunological memory even in infants who are vaccinated at 2, 3 and 4 months of age. Cross-protection does not occur and travellers already immunized with conjugate vaccine against serogroup C are not protected against other serogroups.

In 2010, a conjugated serogroup A meningococcal vaccine designed particularly for use in the African "meningitis belt" received regulatory approval in India and in a few African countries. This vaccine, which is licensed for single-dose immunization of individuals 1–29 years of age, has proved to be safe and highly immunogenic. The conjugate MenA vaccine has been used in large vaccine campaigns in Burkina Faso, Mali and Niger and is being progressively introduced in countries of the African meningitis belt.

Two tetravalent conjugate vaccines against serogroups A, C, Y and W-135 have been licensed in North America and are gradually becoming available in several other countries. In the United States and Canada these vaccines are licensed for individuals 2–55 years of age. A two-dose series of one of these vaccines is licensed also for children aged 9–23 months. These vaccines are expected to induce protection of similar efficacy to, but of longer duration than, that induced by the polysaccharide tetravalent meningococcal vaccine.

Vaccine types available for vaccination / immunisation (uk) / immunization (us) :

Vaccine Against Disease Age D
Dose schedule Price
Live attenuated
MMR vaccine ≥12m 1 $70/=
Measles virus Measles
Mumps virus Mumps
Rubella virus Rubella
Varilrix™ Varicella zoster virus
Varicella Chickenpox 12m-12y 1 $95/=
≥13y 2 6-10w interval
Zostavax™ Herpes zoster Shingles ≥50y 1 $295/=
Stamaril® Yellow fever virus Yellow fever 9m-59y 1 10 yearly $250/=
Inactivated / Whole / Viral & Bacterial
Rabipur® Rabies virus Rabies any 3 d 0, 7, & 21 or 28 $call/=
Ixiaro® Japanese encephalitis virus Japanese encephalitis ≥17y 2 2nd: 28d after 1st $386/=
1 Booster: 12-24m after 2nd
Dukoral® Vibrio cholerae Cholera 2-6y 3 1-6w interval $113/=
1 Booster: 6m after 3rd
≥6y 2 1-6w interval
1 Booster: 2y after 2nd
Inactivated / Fractional / Protein
Intanza™ Influenza virus Influenza 18-59y 1 1 yearly $30/=
Fluarix™ Influenza virus Influenza 6-36m ½ 1 yearly $30/=
>3y 1
Tetavax Clostridium tetani Tetanus adults 3 1-2m interval
3rd @ 6-12m
after 2nd
booster 1 10 yearly
Boostrix® ≥4y 1 <10 yearly $70/=
Corynebacterium diphtheriae Diphtheria
Clostridium tetani Tetanus
Bordetella pertussis Pertussis
Whooping cough
Inactivated / Fractional / Polysaccharide / Pure
Typhim Vi® Salmonella typhi Typhoid fever >5y 1 3 yearly $48/=
Mencevax® ACWY Neisseria meningitidis
types A, C, W-135
and Y
Meningococcal meningitis >2y 1 $80/=
Inactivated / Fractional / Polysaccharide / Conjugate
Menactra® Neisseria meningitidis
types A, C, W-135
and Y
Meningococcal meningitis 2-55y 1 $195/=
Prevenar 13® (SG) /
Prevnar 13® (US)
Streptococcus pneumoniae
types 1, 3, 4, 5,
6A, 6B, 7F, 9V, 14,
18C, 19A, 19F, 23F
Pneumococcal infection 6w-6m 4 1m interval
4th @ 12-15m
7-11m 2 1m interval
12-23m 2 2m interval
2-5y 1
≥50y 1

If the clinic attendance is just for vaccination alone, no additional consultation fees are charged.

Testing for immunity against the following is available:

Virus Antibody Test Price
Varicella zoster virus Varicella Zoster IgG Antibody $44/=
Measles virus Measles IgG Antibody $90/=
Rubella virus Rubella IgG Antibody $24/=
Hepatitis A virus Hepatitis A IgG Antibody $30/=
Hepatitis B virus Hepatitis B surface Antibody $10/=

Other vaccines not stocked

References Vaccine Classification References Hajj vaccine / Haj vaccine / Umrah vaccine requirements for travel to Mecca, Saudi Arabia: References STD vaccine / hepatitis vaccine shot/jab/injection to prevent some STDs

Vaccine Against Disease Age D
Dose schedule Price
Havrix™ 1440 Adult Hepatitis A virus Hepatitis A ≥19y 2 m 0 & 6-12 $90/=
Twinrix® Hepatitis A virus
Hepatitis B virus
Hepatitis A
Hepatitis B
1-15y 2 m 0, 6-12 $135/=
≥16y 3 m 0, 1, 6
4 d 0, 7, 21 & m 12
Inactivated / Fractional / Protein / Subunit / Recombinant
Engerix™-B 20 μg Hepatitis B virus Hepatitis B 11-15y 2 m 0, & 6 $50/=
≥20y 3 m 0, 1, & 6
4 m 0, 1, 2, & 12 or
d 0, 7, 21 & m 12
Gardasil® HPV
types 6, 11, 16, & 18
Genital warts
Cervical cancer
9-26y 3 m 0, 2, & 6 or
m 0, 1, & 4
Cervarix® HPV
types 16, & 18
(31, 33, & 45)
10-25y 3 m 0, 1, & 6
m 0, 1, & 5
m 0, 2½, 12
V503 HPV
types 6, 11, 16, 18,
31, 33, 45,
52, & 58
3 m 0, 2, & 6 or
m 0, 1, & 4

Vaccine schedule / vaccination schedule / immunisation schedule / immunization schedule :

Annex A

National Childhood and Adolescent Immunisation Schedule, Singapore
For persons aged 0 to <18 years

Vaccination against Birth 1 month 3 months 4 months 5 months 6 months 12 months 15 months 18 months 6-7 years^ 10-11 years^^
Tuberculosis BCG
Hepatitis B HepB (D1) HepB (D2) HepB (D3)#
Diphtheria, Tetanus, Pertussis DTaP (D1) DTaP (D2) DTaP (D3) DTaP (B1) Tdap (B2)
Poliovirus OPV (D1) OPV (D2) OPV (D3) OPV (B1) OPV (B2) OPV (B3)
Measles, Mumps, Rubella MMR (D1) MMR (D2)##
Pneumococcal Disease PCV (D1) PCV (D2) PCV (B1)
Human Papillomavirus Recommended for females 9 to 26 years; three doses are required at intervals of 0, 2, 6 months
Influenza Recommended annually for all children aged 6 months to <5 years and children aged 6 months to <18 years in high-risk groups

BCG Bacillus Calmette-Guérin
HepB Hepatitis B vaccine
DTaP Paediatric diphtheria and tetanus toxoid and acellular pertussis vaccine
Tdap Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine
MMR Measles, mumps, and rubella vaccine
OPV Oral polio vaccine
PCV Pneumococcal conjugate vaccine
D1/D2/D3 1st dose, 2nd dose, 3rd dose
B1/B2/B3 1st booster, 2nd booster, 3rd booster
^ Primary 1
^^ Primary 5
# 3rd dose of HepB can be given with the 3rd dose of DTaP and OPV for the convenience of parents.
## 2nd dose of MMR can be given between 15-18 months


We offer teenage, adult and travel vaccination. Vaccines from the above list that we have are: