Sun Feb 5 00:29:19 SGT 2012  
    SHIM CLINIC
STD CLINIC SINGAPORE™
168 Bedok South Avenue 3 #01-473
Singapore 460168
Tel: (+65) 6100 7446 (SHIM)
Fax: (+65) 6449 7446
24hr Answering Tel: (+65) 6333 5550
Opening Hours
Monday to Friday: 9 am to 3 pm, 7 pm to 11 pm
Saturday & Sunday: 7 pm to 11 pm
Public Holidays: Closed
Walk-in clinic. Appointments not required.
Bring NRIC, Work Pass or Passport for registration.

Hepatitis B | Shim Clinic, STD CLINIC SINGAPORE™

Share |
Summary

Hepatitis B | Shim Clinic, STD CLINIC SINGAPORE™: Hepatits B - symptoms in men/women, screening/diagnosis, testing/check, treatment clinic, Singapore - Private and confidential service. Definitions, references, and latest news.

Description

Contents

Hepatitis B infection is caused by the Hepatitis B virus and is usually screened for by detecting HBsAg in the blood. Immunity may be discerned by detecting HBsAb, and if absent, the Hepatitis B vaccine or Twinrix® vaccine may be given.

  • The hepatitis B virus is 100 times more infectious than HIV, the virus that causes AIDS, and infects about 10 times more people than HIV worldwide.
  • Hepatitis B virus infects the liver, and more than 350 million people in the world are lifelong hepatitis B virus carriers.
  • Long-term hepatitis B virus infection causes at least one million premature deaths every year from cirrhosis of the liver or liver cancer. It is second only to tobacco as the leading cause of cancer in humans.
  • Among the Hepatitis B carriers, 25% will develop serious liver diseases, including chronic hepatitis, cirrhosis, and hepatocellular carcinoma.
  • The hepatitis B virus can be passed from an infected mother to her baby during childbirth, 1 in 20 Singaporeans are chronically infected with hepatitis B virus.
Virology and Immunology

Abbreviation Name Presence in blood indicates
HBsAg Hepatitis B Surface Antigen
(Australia antigen)
Carrier
HBsAb Hepatitis B Surface Antibody Immunity
HBeAg Hepatitis B Envelope Antigen Infectivity/Activity
HBeAb Hepatitis B Envelope Antibody Favourable prognosis
HBcAg Hepatitis B Core Antigen Not detectable in blood
Detectable in liver biopsy
HBcAb Hepatitis B Core Antibody HBsAb presence
due to infection
Blood testing is available for all the above except HBcAg

Treatment

  • Nucleoside analog reverse transcriptase inhibitors
  • Nucleotide analog reverse transcriptase inhibitors

TORCHES

TORCHES is a medical acronym for a set of perinatal infections (i.e. infections that are passed from a pregnant woman to her fetus), that can lead to severe fetal anomalies or even fetal loss.
Other agents are:

STD vaccine / hepatitis vaccine shot/jab/injection to prevent some STDs

Vaccine Against Disease Doses
req'd
Dose schedule Price
per
dose
(SG$)
Hepatitis A vaccine Hepatitis A virus Hepatitis A 2 mo. 0 & 6 $90/=
Hepatitis B vaccine Hepatitis B virus Hepatitis B 3-4 mo. 0, 1, & 6 or
mo. 0, 1, 2, & 12 or
d. 0, 7, 21 & mo. 12
$50/=
Twinrix® Hepatitis A virus
Hepatitis B virus
Hepatitis A
Hepatitis B
3-4 mo. 0, 1, & 6 or
d. 0, 7, 21 & mo. 12
$120/=
Gardasil® -
HPV vaccine
HPV
types 6, 11, 16 and 18
Genital warts
Cervical cancer
3 mo. 0, 2, & 6 or
mo. 0, 1, & 4
$195/=
Cervarix® -
HPV vaccine
HPV
types 16 and 18
(31, 33, and 45)
Genital warts
Cervical cancer
3 mo. 0, 1, & 6 $195/=
V503 -
HPV vaccine
HPV
types 6, 11, 16, 18,
31, 33, 45,
52, and 58
Genital warts
Cervical cancer
3 mo. 0, 2, & 6 or
mo. 0, 1, & 4
$???/=

References

References


Latest News

An improved reverse dot hybridization for simple and rapid detection of adefovir dipivoxil-resistant hepatitis B virus.
Fri, 03 Feb 2012 11:24:05 +0100 | Genetics and Molecular Research
An improved reverse dot hybridization for simple and rapid detection of adefovir dipivoxil-resistant hepatitis B virus. Genet Mol Res. 2012;11(1):53-60 Authors: Hu Y, Zhang WL, Xie SL, Zhao Y, Hu JL, Cai XF, Lai GQ, Huang AL Abstract Early detection of adefovir dipivoxil-resistant mutants during long-term treatment of chronic hepatitis B virus (HBV) infection with this drug is of great clinical importance. We developed an improved reverse dot hybridization test for simple and rapid detection of the rtA181V/T and rtN236T mutations associated with adefovir dipivoxil resistance in chronic hepatitis B patients. Probes were designed for genotypes B, C, and D of this resistance characteristic; a total of 70 clinical samples were analyzed with this improved reverse dot hybridizati...

Nigeria: Dismal State of Hepatitis B Management in Country
Fri, 03 Feb 2012 08:24:50 +0100 | AllAfrica News: Health and Medicine
[Daily Trust] Let me start by declaring that I am writing under a pseudonym as I cannot stand the social implication of disclosing my health details in a public medium like this. (Source: AllAfrica News: Health and Medicine)

Well: HPV Vaccine Now Recommended for Boys, Hepatitis B Vaccine for Diabetes
Fri, 03 Feb 2012 03:29:32 +0100 | NYT Health
Federal health officials recommended this week that all boys be routinely vaccinated against human papillomavirus, or HPV, and that people with diabetes be vaccinated against hepatitis B. (Source: NYT Health)

Well Blog: HPV Vaccine Now Recommended for Boys, Hepatitis B Vaccine for Diabetes
Thu, 02 Feb 2012 16:59:25 +0100 | NYT Health
Federal health officials recommended this week that all boys be routinely vaccinated against human papillomavirus, or HPV, and that people with diabetes be vaccinated against hepatitis B. (Source: NYT Health)

Recommendations For HPV And Hepatitis B Vaccinations Broadened By 2012 Adult Immunization Schedule
Thu, 02 Feb 2012 09:00:00 +0100 | Health News from Medical News Today
The CDC's Advisory Committee on Immunization Practices (ACIP) now recommends routine HPV vaccination for males aged 11 to 12 years and catch-up vaccination for males aged 13 to 21. These are just two of the changes to the 2012 Recommended Adult Immunization Schedule published February 1 in Annals of Internal Medicine, the flagship journal of the American College of Physicians (ACP). In addition to the changes in the HPV vaccine, the ACIP now recommends vaccination against Hepatitis B for adults younger than age 60 who have diabetes, as soon as possible after diabetes is diagnosed... (Source: Health News from Medical News Today)

The HBV Vaccination in Adults With Diabetes MellitusThe HBV Vaccination in Adults With Diabetes Mellitus
Thu, 02 Feb 2012 04:00:00 +0100 | Medscape Today Headlines
How important is it for patients with diabetes to be vaccinated against hepatitis B? This new report explains. Morbidity & Mortality Weekly Report (Source: Medscape Today Headlines)

Cost Effectiveness of Screening Immigrants for Hepatitis BCost Effectiveness of Screening Immigrants for Hepatitis B
Thu, 02 Feb 2012 04:00:00 +0100 | Medscape Today Headlines
Are hepatitis B screening programs for new immigrants necessary and cost-effective? This new study explores the issue. Liver International (Source: Medscape Today Headlines)

2012 adult immunization schedule broadens recommendations for HPV and hepatitis B vaccinations
Wed, 01 Feb 2012 05:00:00 +0100 | EurekAlert! - Medicine and Health
(American College of Physicians) The CDC's Advisory Committee on Immunization Practices now recommends routine HPV vaccination for males aged 11-12 years and catch-up vaccination for males aged 13-21. These are just two of the changes to the 2012 Recommended Adult Immunization Schedule being published Feb. 1 in Annals of Internal Medicine. (Source: EurekAlert! - Medicine and Health)

Brain metastases from hepatocellular carcinoma: Clinical features and prognostic factors
Wed, 01 Feb 2012 05:00:00 +0100 | BMC Cancer
Conclusions: BM from HCC is rare and associated with an extremely poor prognosis. However, patients with a low RPA class may benefit from aggressive treatment. The clinical implication of extracranial metastases in HCC patients with BM needs further assessment. (Source: BMC Cancer)


ABOUT TRUST ONLINE