Gonorrhoea | Shim Clinic, STD CLINIC SINGAPORE™

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Summary

Gonorrhoea | Shim Clinic, STD CLINIC SINGAPORE™: Gonorrhoea/Gonorrhea symptoms in men/women, screening/diagnosis, testing/check, treatment clinic, Singapore - Private and confidential service. Definitions, references, and latest news.

Description

Gonorrhoea (UK spelling) / gonorrhea (US spelling) is caused by Neisseria gonorrhoeae, a Gram-negative intracellular diplococci, and is usually treated with Ceftriaxone injection.

The signs of gonorrhoea appear between 2-10 days after sexual contact with an infected person.

These include:

• pus discharge from the penis
• yellow, bloody vaginal discharge
• painful burning sensation during urination.

The signs of gonorrhoea may disappear without treatment, but the germs are still present in the body.

If not treated, gonorrhoea may lead to:

• Infertility - Gonorrhoea may damage the reproductive organs.
• Blindness in the newborn - During childbirth, an infected mother can pass gonorrhoea to her newborn baby, causing eye infection.

References

• Gonorrhoea - Wikipedia, the free encyclopedia
• Gonorrhoea: Definition from Answers.com
• Gonorrhoea - definition of Gonorrhoea in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia.
• WHO | Management of gonorrhoea and Chlamydia trachomatis infections in pregnancy
• Gonorrhea - STD information from CDC

Appropriate Time for Test-of-Cure when Diagnosing Gonorrhoea with a Nucleic Acid Amplification Test.
Mon, 30 Jan 2012 05:00:00 +0100 | Acta Derm Venereol A...
Authors: Hjelmevoll SO, Olsen ME, U J, Haaheim H, Melby KK, Moi H, Unemo M, Skogen V Abstract Culture is commonly regarded as the gold standard for diagnosis of Neisseria gonorrhoeae. However, nucleic acid amplification tests (NAATs) have rapidly replaced culture for diagnostics in many settings. The aim of the present study was to investigate the appropriate time for test-of-cure (TOC) when NAATs are used for diagnosis of gonorrhoea. In total, 30 patients (28 men and 2 women) provided urethral, cervical, rectal or pharyngeal specimens for TOC. All included patients, except one who did not return for second TOC before day 19, tested negative within 2 weeks after treatment with cefixime 400 mg × 1. Antimicrobial susceptibility testing showed that 68% of the culture-positive str...

The role of sexually transmitted infections in the evolution of the South African HIV epidemicRôle des infections sexuellement transmissibles dans l’évolution de l’épidémie du VIH en Afrique du sudEl papel de las infecciones de transmisión sexual en la evolución de la epidemia de VIH en Sudáfrica
Thu, 19 Jan 2012 09:54:07 +0100 | Tropical Medicine and International Health
Conclusions  Sexually transmitted infections have contributed significantly to the spread of HIV in South Africa, but STI control efforts have had limited impact on HIV incidence because of their late introduction and suboptimal coverage.Objectifs:  Evaluer la mesure dans laquelle les infections sexuellement transmissibles (IST) ont contribuéà la propagation du VIH en Afrique du sud et estimer dans quelle mesure des améliorations dans le traitement des IST ont réduit l’incidence du VIH.Méthodes:  Un modèle mathématique a été utilisé pour simuler les interactions entre le VIH et six autres IST (herpès génital, syphilis, chancre mou, blennorragie, infection à Chlamydia et à Trichomonas) ainsi que la vaginose bactérienne et la candidose vaginale. Les effets des IST sur ...

Highlights from this issue
Sun, 15 Jan 2012 05:00:00 +0100 | Sexually Transmitted Infections
New approaches to partner notification have emerged over the past decade. This month we publish the clinical and economic results of a trial of ‘Accelerated Partner Therapy’, a form of expedited partner therapy adapted to the legislative framework of the UK.1 An editorial by Dombrowski and Golden2 provides a perspective from ‘across the pond’ on the potential of Accelerated Partner Therapy. Policymakers and practitioners will always have to adapt partner notification practice to local professional and cultural contexts, so it is good to see new models of partner notification emerging that may serve the needs of countries where straightforward patient delivered therapy is not approved. We are pleased to include an editorial this month by David Gurnham, an academic la...

Is Accelerated Partner Therapy (APT) a cost-effective alternative to routine patient referral partner notification in the UK? Preliminary cost-consequence analysis of an exploratory trial
Sun, 15 Jan 2012 05:00:00 +0100 | Sexually Transmitted Infections
Conclusion The hotline strategy costs more than both the alternative PN strategies. If we accept that strategies which identify and treat partners the fastest are likely to be the most effective in reducing reinfection and onward transmission, then APT Hotline appears an effective PN strategy by treating the highest number of partners in the shortest duration. Whether the additional benefit is worth the additional cost cannot be determined in this preliminary analysis. These data will be useful for informing development of future randomised controlled trials of APT. (Source: Sexually Transmitted Infections)

2011's best health news
Thu, 29 Dec 2011 12:43:00 +0100 | NHS News Feed
Although Behind the Headlines often spends time explaining mistaken or misguided news reports, the joy of this service is when there are genuinely exciting medical advances to report. Over the past year there have been many important and fascinating stories, and it is a credit to the national press that so many of them have been so well understood and so well reported. Here’s our pick of some of the best stories from the many brilliant health articles and impressive studies published in 2011.   Heartwarming gene therapy By far the most heartwarming breakthrough in medical science involves the story of seven-year-old Jack Crick (presumably no relation to the co-discoverer of the DNA double helix). Jack was born with severe combined immunodeficiency (SCID) – an inherited genetic mutati...

Gonorrhoea - the drugs don't work
Fri, 23 Dec 2011 08:41:37 +0100 | BBC News | Health | UK Edition
Why funding for research into new drugs to treat gonorrhoea is "crucial" (Source: BBC News | Health | UK Edition)

High-level cefixime- and ceftriaxone-resistant N. gonorrhoeae in Europe (France): novel penA mosaic allele in a successful international clone causes treatment failure.
Mon, 12 Dec 2011 05:00:00 +0100 | Antimicrobial Agents and Chemotherapy
Authors: Unemo M, Golparian D, Nicholas R, Ohnishi M, Gallay A, Sednaoui P Abstract Recently, the first Neisseria gonorrhoeae strain (H041) highly resistant to the extended-spectrum cephalosporins (ESC) ceftriaxone and cefixime, which are the last remaining options for first-line gonorrhoea treatment, was isolated in Japan. Here, we confirm and characterize a second strain (F89) with high-level cefixime and ceftriaxone resistance, which was isolated in France and most likely caused a treatment failure with cefixime. F89 was examined using six species-confirmatory tests, antibiograms (33 antimicrobials), porB sequencing, N. gonorrhoeae multiantigen sequence typing (NG-MAST), multilocus sequence typing (MLST), and sequencing of known gonococcal resistance determinants (penA, mtrR, pe...

An audit of treatment and follow-up of patients diagnosed with genital Gonorrhoea in South Warwickshire GUM department: Category: Lesson in Microbiology & Infection Control
Fri, 25 Nov 2011 11:05:46 +0100 | Journal of Infection
N.Gonorrhoeae is a gram negative intracellular diplococcus. In the GUM department it is detected by microscopy and/or culture after a sexual history and examination with relevant swab taking. (Source: Journal of Infection)

First Neisseria gonorrhoeae strain with resistance to cefixime causing gonorrhoea treatment failure in Austria, 2011.
Sun, 20 Nov 2011 16:42:03 +0100 | Euro Surveill
Authors: Unemo M, Golparian D, Stary A, Eigentler A PMID: 22085601 [PubMed - in process] (Source: Euro Surveill)