Genital Warts Singapore Clinic

Genital Warts Singapore Clinic: Genital warts (condyloma, condylomata acuminata, venereal wart, anal wart, anogenital wart, "cauliflower" sex disease) symptoms in men/women, screening/diagnosis, testing/check, treatment clinic, Singapore - Private and confidential service. Definitions, references, and latest news.

Description

Table of Contents

• Human papillomavirus (HPV)
• Genital warts
• HPV vaccine
  • Gardasil®
  • Cervarix®
• HPV test

Genital warts appear within 3 months after sexual contact with an infected person.

Genital warts:

• are usually soft, pink cauliflower-like growths or flesh-coloured bumps on the sex organs
• may also be hard and smooth
• occur alone or in groups
• tend to recur after treatment
• increase the risk of cervical cancer in women.

A person with genital warts can infect others through sexual contact.

The majority of genital warts is caused by the human papillomavirus (HPV) types 6 and 11. It is usually treated by cryosurgery with liquid nitrogen. Prevention is possible with a HPV vaccine like Gardasil®.

Human papillomavirus (HPV) There are nearly 200 known types of HPV. They cause

• 100% of genital warts
• 100% of cervical cancers in females,
• 90% of anal cancers in males & females
• 40% of external genitalia cancers
  • penile cancers in males,
  • vulvar cancers in females,
  • vaginal cancers in females,
• 12% of oropharyngeal cancers (mouth and throat cancers)
• 3% of oral cancers

• HPV types 1 and 2 cause plantar warts
• HPV types 3 and 10 cause flat warts
• HPV types 6 and 11 (preventable with Gardasil® vaccination) cause 90% of genital warts
• HPV types 16 and 18 (preventable with Gardasil® or Cervarix® vaccination) cause 70% of cervical cancers in females,
• HPV types 16, 18, 31, 33, 45, 52, and 58 (preventable with nine-valent vaccination cause the majority of cervical cancers in females

HPV vaccine (previous known as cervical cancer vaccine) types:

• Gardasil® [HPV (Human Papillomavirus) Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant]
• Cervarix® [HPV (Human Papillomavirus) Bivalent (Types 16 and 18) Vaccine, Recombinant]
• nine-valent [HPV (Human Papillomavirus) Nonavalent (Types 6, 11, 16, 18, 31, 33, 45, 52, and 58) Vaccine, Recombinant] - to be released in 2013

• 2006 June 8th - US FDA approves use in females aged 9 to 26 years
• 2006 - Singapore HSA approval
• 2009 January 9th - Merck applying for use in females aged 27 to 45 years
• 2009 October 16th - US FDA approves use in males aged 9 to 26 years
• If this trend continues, we would likely see it being approved for used in males aged 27 to 45 years.
• Check our vaccines page for the price, doses required and dose sechedule.

• 2007 - Singapore HSA approval
• 2009 October 16th - US FDA approves use in females aged 10 to 25 years

References

• Genital warts - Wikipedia, the free encyclopedia
• Genital warts: Definition from Answers.com
• Genital warts - definition of Genital warts in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia.

An HPV vaccine cheap enough for the developing world? Could be
Thu, 29 Jul 2010 07:42:52 +0100 | ScienceDaily Headlines
Vaccine manufacturers in India and other developing countries may be able to produce a lower-cost HPV vaccine in spite of the complicated array of patent protections on the technology, say researchers. (Source: ScienceDaily Headlines)

Combined antioxidant carotenoids and the risk of persistent human papillomavirus infection.
Thu, 29 Jul 2010 00:40:05 +0100 | Nutrition and Cancer
Authors: Peterson CE, Sedjo RL, Davis FG, Beam CA, Giuliano AR Persistent infection with human papillomavirus (HPV) is the primary etiologic factor for cervical cancer. The synergistic effect of carotenoids on HPV persistence has not been examined. To explore these potential synergies, we developed 2 measures of carotenoid status using circulating and dietary intake nutrients in which each nutrient was given equal weighting. We then compared persistent HPV infection with its counterpart, intermittent infection. In the analysis using the Crude Index, no association was observed between circulating nutrients and persistent infection with oncogenic HPV [odds ratio (OR)(adjusted) = 0.8, 95% confidence interval (CI) = 0.3-2.2)] or any type HPV (OR(adjusted) = 0.8, 95% CI = 0.3-2.1). Similar...

Experts Concerned About Increase In HPV-Related Head And Neck Cancers
Wed, 28 Jul 2010 10:00:00 +0100 | Health News from Medical News Today
The human papillomavirus increasingly is being identified as the cause of head and neck cancers, prompting some physicians to guess that the genesis of the cancers might be oral sex, the Raleigh News & Observer reports. David Brizel, an oncologist at Duke University who specializes in head and neck cancers, said, "A third of head and neck cancers we see nowadays are [related to] HPV." Although few studies have established a direct link between oral sex, through which HPV can be transmitted, and head and neck cancers, recent studies published in both European and U.S... (Source: Health News from Medical News Today)

Zetiq Reports CE Conformity For Its Cervical Cancer Diagnostic Kit
Wed, 28 Jul 2010 08:00:00 +0100 | Health News from Medical News Today
Zetiq Technologies Ltd. ("Zetiq"), a subsidiary of Bio-Light Ltd. (TASE: BOLT), reports that it has fulfilled the essential requirements towards issuing a self declaration CE mark of conformity for its diagnostic product for identification of cervical cancer in cytological specimens. The requirements fulfilled by the company comply with Council Directive 98/79/EEC for in vitro diagnostic medical devices. As part of these requirements, the Zetiq laboratory has recently received an ISO 13485: 2003 certificate for developing and manufacturing medical products... (Source: Health News from Medical News Today)

Prevalence, concordance and determinants of human papillomavirus infection among heterosexual partners in a rural region in central Mexico
Tue, 27 Jul 2010 23:00:00 +0100 | BMC Infectious Diseases
Conclusions: In heterosexual couples in rural regions in Mexico, the prevalence of HPV infection and type-specific concordance is high. High-risk sexual behaviors are strong determinants of HPV infection in men. (Source: BMC Infectious Diseases)

Polymorphism in exon 4 of TP53 gene associated to HPV 16 and 18 in Mexican women with cervical cancer
Tue, 27 Jul 2010 09:29:13 +0100 | Medical Oncology
Abstract  Cervical cancer (CC) is the second most common cancer in Mexican women. Human papillomavirus (HPV) infection is necessary but not sufficient for CC development. Furthermore, genetic factors as polymorphisms could be important susceptibility factors. Controversial results regarding TP53 polymorphisms specifically in codon 72 of CC have been reported. In the present work, the exon 4 sequence of TP53 gene in CC and healthy Mexican-mestizo women were analyzed. A group of 111 women with CC and 126 healthy women (control) were included. Peripheral blood cells for polymorphism analysis and cervical scrape for HPV detection were used. PCR of exon 4 of TP53 were subjected to denaturing high-performance liquid chromatography (DHPLC) analysis and sequencing. HPV detection was ...

Giant magnetoimpedance-based microchannel system for quick and parallel genotyping of human papilloma virus type 16/18
Tue, 27 Jul 2010 07:51:05 +0100 | Applied Physics Letters
Hao Yang, Lei Chen, Chong Lei, Ju Zhang, Ding Li et al. Quick and parallel genotyping of human papilloma virus (HPV) type 16/18 is carried out by a specially designed giant magnetoimpedance (GMI) based microchannel system. Micropatterned soft magnetic ribbon exhibiting large GMI ratio serves as the biosensor element. HPV genotyping can be determined by t ... [Appl. Phys. Lett. 97, 043702 (2010)] published Mon Jul 26, 2010. (Source: Applied Physics Letters)

Association between smoking and genital warts: longitudinal analysis
Mon, 26 Jul 2010 14:48:50 +0100 | Sexually Transmitted Infections
Conclusions Smokers experienced a moderately increased risk of being diagnosed with genital warts. This finding could be explained by the immunosuppressive effects of nicotine, or by confounding not accounted for in the adjusted model. (Source: Sexually Transmitted Infections)

Einstein Receives $4 Million To Test HPV Microbicide
Sun, 25 Jul 2010 08:00:00 +0100 | Health News from Medical News Today
The National Cancer Institute has awarded Albert Einstein College of Medicine of Yeshiva University $4.1 million to test the microbicide Carraguard® against the human papillomavirus (HPV), which causes cervical cancer. The research will evaluate the efficacy of Carraguard®, a clear gel made from the seaweed derivative carrageenan in preventing new HPV infections in women. According to the World Health Organization, approximately 440 million males and females are infected with HPV worldwide. The Centers for Disease Control estimates at least 20 million Americans have HPV... (Source: Health News from Medical News Today)