Thu May 17 20:51:24 SGT 2012  
SHIM CLINIC
MEN'S CLINIC SINGAPORE™
168 Bedok South Avenue 3 #01-473
Singapore 460168
Tel: (+65) 6100 7446
Fax: (+65) 6449 7446
24hr Answering Tel: (+65) 6333 5550
Web: www.ShimClinic.com
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Saturday & Sunday: 7 pm to 11 pm
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Erectile Dysfunction Treatment | Shim Clinic, MEN'S CLINIC SINGAPORE™

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Summary

Erectile Dysfunction Treatment | Shim Clinic, MEN'S CLINIC SINGAPORE™: Male impotence, sexual/erectile dysfunction (ED) symptoms, treatment, drugs/medication clinic, Singapore. Private and confidential service. Definitions, references, and latest news.

Description

Table of Contents

Erectile dysfunction treatment is frequently done with the prescription of erectile dysfunction drugs which are usually phosphodiesterase type 5 (PDE5) inhibitors like:

Erectile dysfunction may be assessed with the international index of erectile function (IIEF-5) a.k.a. sexual health inventory for men (SHIM), and an erectile dysfunction diagnosis made:

The IIEF-5 questionnairea
Over the past six months:
1 How do you rate your confidence that you could get and keep an erection? Very low Low Moderate High Very high
12345
2 When you had erections with sexual stimulation, how often were your erections hard enough for penetration? Almost never/never A few times (much less than half the time) Sometimes (about half the time) Most times (much more than half the time) Almost always/always
12345
3 During sexual intercourse, how often were you able to maintain your erection after you had penetrated (entered) your partner? Almost never/never A few times (much less than half the time) Sometimes (about half the time) Most times (much more than half the time) Almost always/always
12345
4 During sexual intercourse, how difficult was it to maintain your erection to completion of intercourse? Extremely difficult Very difficult Difficult Slightly difficult Not difficult
12345
5 When you attempted sexual intercourse, how often was it satisfactory for you? Almost never/never A few times (much less than half the time) Sometimes (about half the time) Most times (much more than half the time) Almost always/always
12345
aThe IIEF-5 score is the sum of the ordinal responses to the five items; thus, the score can range from 5 to 25.
ED severity: severe (5-7), moderate (8-11), mild to moderate (12-16), mild (17-21), and no ED (22-25)

Men's health issues:

References
Latest News

Inhibitory effects of phosphodiesterase 5 inhibitor, ---------, on mechanosensitive bladder afferent nerve activities of the rat, and on acrolein‐induced hyperactivity of these nerves
Wed, 16 May 2012 14:16:43 +0100 | BJU International
CONCLUSION• Our study shows, using selective unifibre potential measurement, that systemic administration of --------- reduces mechanosensitive afferent activities of both Aδ‐ and C‐fibres elicited by bladder distension in the rat, and also that --------- has an inhibitory effect on the increased activities of both fibres induced by intravesical acrolein instillation. (Source: BJU International)

Hyperthyroidism linked to erectile dysfunction (AlphaGalileo, 9 May 2012)
Wed, 16 May 2012 12:00:00 +0100 | Society for Endocrinology
Findings from two European studies presented at the joint International Congress of Endocrinology and European Congress of Endocrinology in Florence, Italy, suggest that men suffering from an overactive thyroid gland are at an increased risk for erectile dysfunction. Full article (Source: Society for Endocrinology)

Detecting internet activity for erectile dysfunction using search engine query data in the Republic of Ireland
Tue, 15 May 2012 23:05:37 +0100 | BJU International
CONCLUSIONS• The advent of recent Internet media campaigns and increasing number of Irish web pages is associated with a significant increase in online activity for ED in the Republic of Ireland.• Novel online technologies appear to provide a useful tool for educating the general public on the symptoms and treatment options available for ED. (Source: BJU International)

The Challenge of Erectile Dysfunction in the Man with Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Sat, 12 May 2012 05:50:21 +0100 | Current Urology Reports
Abstract  Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), also known as NIH category III prostatitis, is common and has significant impact on quality of life through pain and lower urinary tract symptoms. A high proportion of men with CP/CPPS suffer from some form of sexual dysfunction including erectile dysfunction, premature ejaculation, and painful ejaculation. While well described, the pathophysiology of these sexual symptoms has not been well studied. This review will focus on what we know regarding the incidence and potential mechanisms for sexual dysfunction in CP/CPPS and discuss diagnostic and therapeutic options. Content Type Journal ArticleCategory Erectile Dysfunction (DK Montague, Section Editor)Pages 1-5DOI 10.1007/s11934-012-0254-0Authors Da...

PDE5 inhibitors, ---------- and ----------, reverse multidrug resistance by inhibiting the efflux function of MRP7 (ABCC10) transporter
Fri, 11 May 2012 04:00:00 +0100 | Cancer Science
SummaryPhosphodiesterase type 5 (PDE5) inhibitors are widely used in the treatment of male erectile dysfunction and in improving the breathing efficiency in pulmonary hypertension. Recently, several groups have evaluated the ability of PDE5 inhibitors for their anticancer activities. Previously, we have shown that ----------, ---------- and --------- could reverse P‐glycoprotein (P‐gp, ABCB1)‐mediated multidrug resistance (MDR). In the present study, we determined whether these PDE5 inhibitors have the potential to reverse multidrug resistance protein 7 (MRP7, ABCC10)‐mediated MDR. We found that ---------- and ---------- dose‐dependently enhanced the sensitivity of MRP7‐transfected HEK293 cells to paclitaxel, docetaxel and vinblastine, while --------- had only minimal effect. A...

Early postoperative pelvic-floor biofeedback improves erectile function in men undergoing radical prostatectomy: a prospective, randomized, controlled trial
Thu, 10 May 2012 04:00:00 +0100 | International Journal of Impotence Research
Authors: C Prota, C M Gomes, L H S Ribeiro, J de Bessa, E Nakano, M Dall'Oglio, H Bruschini & M Srougi (Source: International Journal of Impotence Research)

How I manage priapism in chronic myeloid leukaemia patients
Thu, 10 May 2012 04:00:00 +0100 | British Journal of Haematology
SummaryPriapism is a rare presenting feature of chronic myeloid leukaemia (CML). It is a urological emergency requiring urgent treatment to prevent long‐term complications, in particular erectile dysfunction. In males with CML, ischaemic priapism is believed to result from hyperleucocytosis and associated leucostasis or hyperviscosity, and is seen in patients presenting with a high white cell count. Increasingly, a combined modality approach is being used to treat CML patients presenting with priapism. This includes systemic therapy with chemotherapy (hydroxycarbamide or tyrosine kinase inhibitors) and therapeutic leukapheresis to reduce the white cell count as well as local intracavernous therapy. This review will examine the literature and discuss the presenting features, investigation...

FDA approves agents for ED, renal angiomyolipomas; OAB agent launched
Tue, 08 May 2012 04:26:59 +0100 | Modern Medicine
The FDA recently approved new treatments for erectile dysfunction and renal angiomyolipomas, and a previously approved agent for overactive bladder has been launched. (Source: Modern Medicine)

Recreational Use of Erectile Dysfunction Medications and Its Adverse Effects on Erectile Function in Young Healthy Men: The Mediating Role of Confidence in Erectile Ability
Tue, 08 May 2012 04:00:00 +0100 | The Journal of Sexual Medicine
Conclusions.  Confidence in erectile abilities mediates the inverse relationship between recreational EDM use and erectile function. Results underscore the possibility that recreational EDM use among healthy young men may lead to psychogenic ED. Additional longitudinal research is necessary to establish a causal link between these variables. Harte CB and Meston CM. Recreational use of erectile dysfunction medications and its adverse effects on erectile function in young healthy men: The mediating role of confidence in erectile ability. J Sex Med **;**:**–**. (Source: The Journal of Sexual Medicine)


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