Cervical Cancer Vaccine Singapore Clinic

Cervical Cancer Vaccine Singapore Clinic: HPV (human papillomavirus), cervical/penile/anal/mouth/throat cancer, genital warts vaccine Gardasil®/Cervarix® jab/shot/injection clinic, Singapore. - Definitions, references, and latest news.

Description

Table of Contents

• HPV (human papillomavirus)
• Genital warts
  • Genital warts treatment
• Cervical cancer
  • Cervical cancer vaccine
• HPV vaccine
  • Gardasil®
  • Cervarix®

• Gardasil® [HPV (Human Papillomavirus) Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant]
• Cervarix® [HPV (Human Papillomavirus) Bivalent (Types 16 and 18) Vaccine, Recombinant]
• nine-valent [HPV (Human Papillomavirus) Nonavalent (Types 6, 11, 16, 18, 31, 33, 45, 52, and 58) Vaccine, Recombinant] - to be released in 2013

• 2006 June 8th - US FDA approves use in females aged 9 to 26 years
• 2006 - Singapore HSA approval
• 2009 January 9th - Merck applying for use in females aged 27 to 45 years
• 2009 October 16th - US FDA approves use in males aged 9 to 26 years
• If this trend continues, we would likely see it being approved for used in males aged 27 to 45 years.
• Check our vaccines page for the price, doses required and dose sechedule.

• 2007 - Singapore HSA approval
• 2009 October 16th - US FDA approves use in females aged 10 to 25 years

• 100% of genital warts
• 100% of cervical cancers in females,
• 90% of anal cancers in males & females
• 40% of external genitalia cancers
  • penile cancers in males,
  • vulvar cancers in females,
  • vaginal cancers in females,
• 12% of oropharyngeal cancers (mouth and throat cancers)
• 3% of oral cancers

• HPV types 1 and 2 cause plantar warts
• HPV types 3 and 10 cause flat warts
• HPV types 6 and 11 (preventable with Gardasil® vaccination) cause 90% of genital warts
• HPV types 16 and 18 (preventable with Gardasil® or Cervarix® vaccination) cause 70% of cervical cancers in females
• HPV types 16, 18, 31, 33, 45, 52, and 58 (preventable with nine-valent vaccination) cause 90% of cervical cancers in females. It may be available by 2013.

• QIAGEN - digene HC2 High-Risk HPV DNA Test - For detection of human papillomavirus infections using hybrid capture 2 technology
  • Detects 13 high-risk HPV types: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68.
  • Unable to differentiate which types are positive.
  • Cost is SG$200/=
• QIAGEN - digene HC2 HPV DNA Test - For detection of human papillomavirus infections
  • Detects 13 high-risk HPV types: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68. And 5 low-risk types: 6, 11, 42, 43, and 44.
  • Unable to differentiate which types are positive.
  • Not available in Singapore. Unlikely to be available in future.
• Hybribio® Real Time PCR HPV Detection Kit
  • Detects 13 high-risk HPV types: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68.
  • Able to differentiate which types are positive.
  • Will be available in Singapore soon.

Genital HPV types, disease caused, vaccine & test coverage:

Cervical cancer is caused by HPV (human papillomavirus).

• 70% of cervical cancers is caused by HPV types 16 & 18. Which may be prevented by vaccination with Gardasil® or Cervarix®.
• 90% cervical cancers is caused by HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58. Which may be prevented by vaccination with nine-valent. It may be available by 2013.

Genital warts appear within 3 months after sexual contact with an infected person.

Genital warts:

• are usually soft, pink cauliflower-like growths or flesh-coloured bumps on the sex organs
• may also be hard and smooth
• occur alone or in groups
• tend to recur after treatment
• increase the risk of cervical cancer in women.

A person with genital warts can infect others through sexual contact.

Genital warts treatment is usually by cryosurgery with liquid nitrogen.

Prevention is possible with a HPV vaccine like Gardasil®, which covers types 6 and 11, as they cause 90% of genital warts.

References

• Cervical cancer vaccine - Wikipedia, the free encyclopedia
• Cervical cancer vaccine: Definition from Answers.com
• Cervical cancer vaccine - definition of Cervical cancer vaccine in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia.
• WHO | Human papillomavirus and HPV vaccines
• WHO | Human papillomavirus infection and cervical cancer
• Vaccines: VPD-VAC/HPV/main page

Influences on Human Papillomavirus Vaccination Status Among Female College Students
Fri, 03 Sep 2010 22:13:25 +0100 | Journal of Women
Journal of Women's Health , Vol. 0, No. 0. (Source: Journal of Women)

Safety and Immunogenicity of the Quadrivalent Human Papillomavirus Vaccine in HIV‐1–Infected Men
Thu, 02 Sep 2010 20:19:57 +0100 | The Journal of Infectious Diseases Latest Issue
Conclusions. The quadrivalent HPV vaccine appears safe and highly immunogenic in HIV‐1–infected men. Efficacy studies in HIV‐1–infected men are warranted. Clinical trials registration. NCT 00513526. (Source: The Journal of Infectious Diseases Latest Issue)

Roberts ME, Gerrard M, Reimer R, Gibbons FX. Mother-Daughter Communication and Human Papillomavirus Vaccine Uptake by College Students. Pediatrics. 2010;125(5):982-989
Wed, 01 Sep 2010 15:03:37 +0100 | PEDIATRICS
(Source: PEDIATRICS)

Human Papillomavirus Vaccination Practices: A Survey of US Physicians 18 Months After Licensure
Wed, 01 Sep 2010 15:03:36 +0100 | PEDIATRICS
CONCLUSIONS: Eighteen months after licensure, the vast majority of pediatricians and family physicians reported offering HPV vaccine. Fewer physicians strongly recommended the vaccine for younger adolescents than for older adolescents, and physicians reported financial obstacles to vaccination. (Source: PEDIATRICS)

Reasons for non-vaccination against HPV and future vaccination intentions among 19-26 year-old women
Tue, 31 Aug 2010 23:00:00 +0100 | BMC Women's Health - Latest articles
Conclusions: Educational interventions may be needed to enhance HPV vaccination rates among 19-26 year-old women, particularly regarding information about vaccine safety, vaccine efficacy, insurance coverage, and the value of vaccination to women in monogamous relationships. (Source: BMC Women's Health - Latest articles)

Half of the nation got sunburnt this year
Tue, 31 Aug 2010 23:00:00 +0100 | OnMedica Latest News
Experts warn of people’s hazardous desire for a tanRelated items from OnMedicaParents unsure of HPV vaccine for daughters Low IQ second strongest predictor of heart diseaseCancer survivors most at risk are more likely to smokeVaccine linked to earlier onset of seizures in Dravet syndromeMost UK malaria is from family visits abroad (Source: OnMedica Latest News)

Is the cervical cancer vaccine good to go?
Mon, 30 Aug 2010 23:32:14 +0100 | The Irish Times - Health
VACCINE DEBATE:The arguments for and against the cervical cancer vaccination programme (Source: The Irish Times - Health)

STD Vaccine Viewed Positively According To Survey Of American Women
Sat, 28 Aug 2010 07:00:00 +0100 | Health News from Medical News Today
Cost but not convenience plays a significant role in attitudes about vaccination for common human papillomaviruses for women over the age of 26, according to the authors of a recent article in the journal Sexual Health. Currently, the two vaccines for human papillomavirus (HPV), which is the primary cause of cervical cancer, are U.S. Food and Drug Administration approved for females from 9 to 26 years of age. The vaccines, Gardasil (Merck and Co.) and Cervarix (GlaxoSmithKline) are under review by the FDA for an older population of women... (Source: Health News from Medical News Today)

Boston Globe Editorial Calls Attention To Unnecessary Pap Tests
Fri, 27 Aug 2010 10:00:00 +0100 | Health News from Medical News Today
Even though an annual Pap test "is a long-standing, if much-dreaded, tradition" for many women, "a high proportion of these tests are unnecessary," according to a Boston Globe editorial. The editorial notes that "[g]uidelines recommend testing every two to three years for women at low risk of cervical cancer," such as women older than age 30 who have had multiple negative tests. According to the editorial, "Once a woman has had several negative tests in a row, the evidence strongly suggests that screening more often than recommended is of little benefit... (Source: Health News from Medical News Today)