Fri Jul 30 16:32:29 SGT 2010  
    SHIM CLINIC
168 Bedok South Avenue 3 #01-473
Singapore 460168
Tel: (+65) 6446 7446
Fax: (+65) 6449 7446
24hr Answering Tel: (+65) 6333 5550
Opening Hours
Monday to Friday: 9 am to 3 pm, 7 pm to 11 pm
Saturday & Sunday: 7 pm to 11 pm
Public Holidays: Closed
Walk-in clinic. Appointments not required.
Bring NRIC, Visit Pass or Passport for registration.

Candidiasis Singapore Clinic

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Summary

Candidiasis Singapore Clinic: Candidiasis - symptoms in men/women, screening/diagnosis, testing/check, treatment clinic, Singapore - Private and confidential service. Definitions, references, and latest news.

Description

Candidiasis (Yeast infection) is usually caused by Candida albicans and is usually treated with Clotrimazole or Tioconazole pessaries in females, or Fluconazole capsules orally.

References


Latest News

Candida africana and its closest relatives
Wed, 28 Jul 2010 23:00:00 +0100 | Mycoses
Candida africana is a recently described opportunistic yeast pathogen that has been linked to vaginal candidiasis. This yeast was first described, in 1995, as atypical chlamydospore-negative Candida albicans strain, and subsequently proposed as a new Candida species on the basis of morphological, biochemical and physiological characteristics clearly different from those of typical C. albicans isolates. Phylogenetic studies based on the comparison of ribosomal DNA sequences demonstrated that C. africana and C. albicans isolates are too closely related to draw any conclusions regarding the status of a new species. Therefore, on the basis of these studies, some authors considered C. africana as a biovar of C. albicans even if genetic differences may be found if additional regions of genomic D...

Evaluation of Antifungal Efficacy of Erbium, Chromium: Yttrium-Scandium-Gallium-Garnet Laser Against Candida albicans
Wed, 28 Jul 2010 12:23:23 +0100 | Photomedicine and Laser Surgery
Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Genotypic and phenotypic properties of Candida parapsilosis sensu strictu strains isolated from different geographic regions and body sites
Tue, 27 Jul 2010 23:00:00 +0100 | BioMed Central
Conclusions: The low number of polymorphic AFLP bands (18 out of 80) obtained for C. parapsilosis isolates is in agreement with the limited sequence variability described for this species. However, when band intensity was included in the analysis, geographical clustering was observed. Expression of virulence factors varied among strains isolated from different geographical regions, with biofilm and proteinase producers more frequently isolated from Hungary and Italy, respectively. (Source: BioMed Central)

Molecular detection and characterisation of fungal heat shock protein 60
Tue, 27 Jul 2010 23:00:00 +0100 | Mycoses
Heat shock proteins (Hsp) are highly conserved molecules, which are both constitutively expressed and up-regulated in response to various stress conditions. In particular, fungal Hsp60 can act as immunodominant antigens and facilitate powerful immunological properties. A possible cellular heat shock response was investigated in eight fungi (Aspergillus fumigatus, Aspergillus terreus, Penicillium chrysogenum, Cladosporium cladosporioides, Scedosporium apiospermum, Trichophyton mentagrophytes, Candida albicans and Saccharomyces cerevisiae). Fully automated RNA extraction was followed by quantitative real-time RT-PCR targeting fungus-specific Hsp60 mRNA and sequencing of the amplicon. Levels of temperature-dependent gene expression were evaluated and rates of similarity and identity were comp...

Comparison and evaluation of a novel bioassay and high-performance liquid chromatography for the clinical measurement of serum voriconazole concentrations
Tue, 27 Jul 2010 23:00:00 +0100 | Mycoses
The aim of this study was to develop and validate a novel bioassay for determining serum voriconazole (VRC) concentrations and to compare its routine clinical performance with that of high-performance liquid chromatography (HPLC). The biological activity of VRC was measured by a plate diffusion assay using a VRC-hypersusceptible Candida kefyr strain. The bioassay's utility was tested by measuring steady-state VRC concentrations in 100 serum probes from VRC-treated patients. The HPLC system used solvent extraction with hexane : dichloromethane followed by reversed-phase HPLC with ultraviolet detection. The intra-day and inter-day accuracy of the bioassay was (Source: Mycoses)

Antifungal activity of tri- and tetra-thioureido amino derivatives against different Candida species
Tue, 27 Jul 2010 23:00:00 +0100 | Mycoses
This study demonstrated that thioureido derivatives exhibited significant antifungal activity against Candida species and that they can be considered as a very promising bioactive lead compound to develop novel antifungal agents. (Source: Mycoses)

Fluconazole Resistance Analysis in Candida Glabrata Isolates from OPC Patients
Tue, 27 Jul 2010 05:41:43 +0100 | Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
Steven A. Mayen, Nathan P. Wiederhold, Tom A. Samuel, William R. Kirkpatrick, Thomas F. Patterson, Spencer W. Redding. University of Texas Health Science Center at San Antonio School of Dentistry (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Synthesis and antimicrobial activity of Ag(I)-N-heterocyclic carbene complexes derived from benzimidazol-2-ylidene
Mon, 26 Jul 2010 23:00:00 +0100 | Applied Organometallic Chemistry
Novel benzimidazol-2-ylidene carbene complexes of Ag(I) were prepared by interaction of the corresponding benzimidazolium salt with Ag2O in dichloromethane. Their structures were characterized by elemental analyses, 1H-NMR, 13C-NMR and IR spectroscopy techniques. All compounds studied in this work were screened for their in vitro antimicrobial activities against the standard strains: Enterococcus faecalis (ATCC 29212), Staphylococcus aureus (ATCC 29213), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853) and the fungi Candida albicans and Candida tropicalis. The new complexes were found to be effective antimicrobial activity against a series of bacteria and fungi. Copyright © 2010 John Wiley & Sons, Ltd. (Source: Applied Organometallic Chemistry)

Epidemiology of Opportunistic Fungal Infections in Latin America
Mon, 26 Jul 2010 21:40:55 +0100 | Clinical Infectious Diseases Latest Issue
Clinical Infectious Diseases, Volume 0, Issue 0, Page 000, Latest Articles. This review discusses the epidemiology of the most clinically relevant opportunistic fungal infections in Latin America, including candidiasis, cryptococcosis, trichosporonosis, aspergillosis, and fusariosis. The epidemiologic features, including incidence, of some of these mycoses are markedly different in Latin America than they are in other parts of the world. The most consistent epidemiologic data are available for candidemia, with a large prospective study in Brazil reporting an incidence that is 3‐ to 15‐fold higher than that reported in studies from North America and Europe. Species distribution also differs: in Latin America, the most common Candida species (other than Candida albicans) causing bl...