Candidiasis | Shim Clinic, STD CLINIC SINGAPORE™

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Summary

Candidiasis | Shim Clinic, STD CLINIC SINGAPORE™: Candidiasis/thrush, fungal/yeast/Candida infection symptoms in men/women, screening/diagnosis, testing/check, treatment clinic, Singapore - Private and confidential service. Definitions, references, and latest news.

Description

Candidiasis/candidosis/moniliasis/oidiomycosis or penile/vaginal/oral thrush is a fungal infection (mycosis) / yeast infection of any of the Candida species, of which Candida albicans is the most common. It is usually treated with Clotrimazole or Tioconazole pessaries in females, or Fluconazole capsules orally.

References

• Candidiasis - Wikipedia, the free encyclopedia
• Candidiasis: Definition from Answers.com
• Candidiasis - definition of Candidiasis in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia.
• Guidelines for the Management of Sexually Transmitted Infections: 3. TREATMENT OF SPECIFIC INFECTIONS: 3.11. Candidiasis
• Disease Listing: Candidiasis General Information | CDC DFBMD

Starmerella bombicola influences the metabolism of Saccharomyces cerevisiae at pyruvate decarboxylase and alcohol dehydrogenase level during mixed wine fermentation
Fri, 03 Feb 2012 05:00:00 +0100 | Microbial Cell Factories
Conclusion: In mixed fermentation, S. bombicola immobilized cells greatly affected the fermentation behavior of S. cerevisiae and the analytical composition of wine. The influence of S. bombicola on S. cerevisiae was not limited to a simple additive contribution. Indeed, its presence caused metabolic modifications during S. cerevisiae fermentation causing variation in the gene expression and enzymatic activity of alcohol deydrogenase and pyruvate decarboxilase. (Source: Microbial Cell Factories)

The Mind Behind the Message: Advancing Theory‐of‐Mind Scales for Typically Developing Children, and Those With Deafness, Autism, or Asperger Syndrome
Fri, 03 Feb 2012 05:00:00 +0100 | Child Development
Children aged 3–12 years (n = 184) with typical development, deafness, autism, or Asperger syndrome took a series of theory‐of‐mind (ToM) tasks to confirm and extend previous developmental scaling evidence. A new sarcasm task, in the format of H. M. Wellman and D. Liu’s (2004) 5‐step ToM Scale, added a statistically reliable 6th step to the scale for all diagnostic groups. A key previous finding, divergence in task sequencing for children with autism, was confirmed. Comparisons among diagnostic groups, controlling age, and language ability, showed that typical developers mastered the 6 ToM steps ahead of each of the 3 disabled groups, with implications for ToM theories. The final (sarcasm) task challenged even nondisabled 9‐year‐olds, demonstrating the new scale’s sen...

The effect of various concentrations of iodine potassium iodide on the antimicrobial properties of mineral trioxide aggregate – a pilot study
Thu, 02 Feb 2012 05:00:00 +0100 | Dental Traumatology
Conclusions: Substitution of IKI solutions (1%, 2%, and 4%) for water did not significantly increase the antimicrobial activity of MTA. (Source: Dental Traumatology)

Killing by neutrophil extracellular traps: fact or folklore?
Thu, 02 Feb 2012 05:00:00 +0100 | Blood
Neutrophil extracellular traps (NETs) are DNA structures released by dying neutrophils and claimed to constitute a new microbicidal mechanism. Killing by NET-forming cells is ascribed to these structures because it is prevented by preincubation with DNase, which has been shown to dismantle NETs, before addition of the target microorganisms. Curiously, the possibility that the microorganisms ensnared in NETs are alive has not been considered. Using Staphylococcus aureus and Candida albicans blastospores, we demonstrate that the microorganisms captured by NETs and thought to be killed are alive because they are released and recovered in cell medium by incubation with DNase. It is concluded that NETs entrap but do not kill microbes. (Source: Blood)

Efficient capture of Candida albicans and zymosan by SIGNR1 augments TLR2-dependent TNF-{alpha} production
Wed, 01 Feb 2012 05:00:00 +0100 | International Immunology
In this study, we explore the impact of SIGNR1 in the recognition of C. albicans/zymosan and the subsequent tumor necrosis factor (TNF)-α production using SIGNR1-transfected RAW264.7 (RAW-SIGNR1) cells and resident peritoneal macrophages. Compared with RAW-control cells, RAW-SIGNR1 cells dramatically enhanced TNF-α production upon the stimulation with heat-killed C. albicans and zymosan. Recognition of microbes via carbohydrate recognition domain (CRD) of SIGNR1 was crucial for the enhanced TNF-α production. Consistently, such an enhancement was significantly decreased by anti-SIGNR1 mAb. Laminarin, antagonistic Dectin-1 ligand, cooperated to further diminish the response, although no effect was observed by itself in RAW-SIGNR1 cells. However, it moderately reduced the re...

Fungi and allergic lower respiratory tract diseases
Wed, 01 Feb 2012 05:00:00 +0100 | Journal of Allergy and Clinical Immunology
Asthma is a common disorder that in 2009 afflicted 8.2% of adults and children, 24.6 million persons, in the United States. In patients with moderate and severe persistent asthma, there is significantly increased morbidity, use of health care support, and health care costs. Epidemiologic studies in the United States and Europe have associated mold sensitivity, particularly to Alternaria alternata and Cladosporium herbarum, with the development, persistence, and severity of asthma. In addition, sensitivity to Aspergillus fumigatus has been associated with severe persistent asthma in adults. Allergic bronchopulmonary aspergillosis (ABPA) is caused by A fumigatus and is characterized by exacerbations of asthma, recurrent transient chest radiographic infiltrates, coughing up thick mucus plugs,...

Triple fungal infection in a patient with liver cirrhosis.
Wed, 01 Feb 2012 05:00:00 +0100 | Annales de Biologie Clinique
We report a case of triple fungal infection including an invasive pulmonary aspergillosis by Aspergillus fumigatus, a candidemia by Candida albicans and a Pneumocystis pneumonia. The overall clinical picture of this patient was liver cirrhosis with medical history of immunosuppressive treatment for Crohn disease and a non-hodgkin lymphoma. There was no antifungal prophylaxis for this patient. Under treatment, the issue was unfavourable with multivisceral failure. PMID: 22294141 [PubMed - as supplied by publisher] (Source: Annales de Biologie Clinique)

Essential Oil of Juniperus communis subsp. alpina (Suter) Čelak Needles: Chemical Composition, Antifungal Activity and Cytotoxicity
Wed, 01 Feb 2012 05:00:00 +0100 | Phytotherapy Research
Essential oils are known to possess antimicrobial activity against a wide spectrum of bacteria and fungi. In the present work the composition and the antifungal activity of the oils of Juniperus communis subsp. alpina (Suter) Čelak were evaluated. Moreover, the skin cytotoxicity, at concentrations showing significant antifungal activity, was also evaluated. The oils were isolated by hydrodistillation and analysed by gas chromatography and gas chromatography–mass spectrometry. Minimal inhibitory concentration (MIC) and minimal lethal concentration (MLC) were used to evaluate the antifungal activity of the oil against dermatophytes (Epidermophyton floccosum, Microsporum canis, M. gypseum, Trichophyton mentagrophytes, T. mentagrophytes var. interdigitale, T. rubrum, T. verrucosum), yeasts ...

An Aspergillus nidulans bZIP response pathway hardwired for defensive secondary metabolism operates through aflR
Tue, 31 Jan 2012 20:34:56 +0100 | Molecular Microbiology
SummaryThe eukaryotic bZIP transcription factors are critical players in organismal response to environmental challenges. In fungi, the production of secondary metabolites (SMs) is hypothesized as one of the responses to environmental insults, e.g. attack by fungivorous insects, yet little data to support this hypothesis exists. Here we establish a mechanism of bZIP regulation of SMs through RsmA, a recently discovered YAP‐like bZIP protein. RsmA greatly increases SM production by binding to two sites in the A. nidulans AflR promoter region, a C6 transcription factor known for activating production of the carcinogenic and anti‐predation SM, sterigmatocystin (ST). Deletion of aflR in an overexpression rsmA (OE::rsmA) background not only eliminates ST production but also significantly re...