Summary
Blemish Singapore Clinic: Liver spots, sun spots, solar lentigo, solar lentigines, age spots, lentigo senilis, senile lentigines, melasma, chloasma faciei, freckles, hyperpigmentation, pigmentation, dark spots removal, treatment clinic, Singapore. Definitions, references, and latest news.
Description
Types of Hyperpigmentation (excessive pigmentation, dark spots)
The best treatments involve inhibiting the production of the skin pigment melanin, encouraging the shedding of the older, outer pigmented layers of skin, and reducing the stimulus for melanin production by protecting the skin from the sun. Methods of treating pigmentation:
Inhibit the production of the skin pigment melanin
Encouraging the shedding of the older, outer pigmented layers of skin Reducing the stimulus for melanin production by protecting the skin from the sun
References
Latest News
Commentary: Treatment of Facial Postinflammatory Hyperpigmentation with Facial Acne in Asian Patients Using a Novel Q‐Switched Neodymium‐Doped Yttrium Aluminum Garnet Laser
Tue, 31 Aug 2010 23:00:00 +0100 | Dermatologic Surgery
Andrei Metelitsa, MD, has indicated no significant interest with commercial supporters (Source: Dermatologic Surgery)
Human Equilibrative Nucleoside Transporter-3 (hENT3) Spectrum Disorder Mutations Impair Nucleoside Transport, Protein Localization, and Stability [Membrane Biology]
Fri, 27 Aug 2010 13:40:49 +0100 | Journal of Biological Chemistry
In this study, we performed functional and biochemical characterization of these mutations in hENT3. We report severe reductions/losses of hENT3 nucleoside transport functions of hENT3 syndrome mutants. In addition to transport alterations, we provide evidence for possible loss of hENT3 functions in all H and pigmented hypertrichotic dermatosis with insulin-dependent diabetes syndromes due to either mistrafficking or altered stability of mutant hENT3 proteins. (Source: Journal of Biological Chemistry)
CASE REPORT: Diltiazem‐associated photodistributed hyperpigmentation: Report of two Japanese cases and published work review
Fri, 27 Aug 2010 05:41:28 +0100 | The Journal of Dermatology
Abstract (Source: The Journal of Dermatology)
Minocycline: Hyperpigmentation in an elderly patient: case report
Mon, 16 Aug 2010 07:07:41 +0100 | Reactions
(Source: Reactions)
Bimatoprost: Periocular skin hyperpigmentation: 4 case reports
Fri, 13 Aug 2010 05:47:51 +0100 | Reactions
(Source: Reactions)
Clinical characteristics of hydroxychloroquine retinopathy.
Fri, 06 Aug 2010 23:00:00 +0100 | The British Journal of Ophthalmology
Conclusions Hydroxychloroquine retinopathy, although rare, still exists despite current screening guidelines. The authors recommend that physicians dose hydroxychloroquine according to lean body weight and that they use risk stratification to guide their screening regimens.
PMID: 20693556 [PubMed - as supplied by publisher] (Source: The British Journal of Ophthalmology)
Review of the Literature: Treatment of Dyspigmentation with Fractionated Resurfacing
Tue, 03 Aug 2010 23:00:00 +0100 | Dermatologic Surgery
Traditional ablative laser resurfacing is associated with adverse side effects, including prolonged erythema, edema, burning, milia, acne, crusting, and hypo- and hyperpigmentation. Fractional photothermolysis (FP) has been introduced to overcome the disadvantages of traditional ablative and nonablative resurfacing. With FP, the microscopic, pixilated pattern of wounding in the dermis results in significant skin pigmentary and textural improvements without the adverse effects of prolonged wound healing and risks of dyspigmentation associated with traditional ablative resurfacing. FP has been reported to improve hypo- and hyperpigmentation in a variety of cutaneous conditions. To review the dermatologic literature on the use of FP for treatment of dyspigmentation. Review of the Medline lite...
Recovery of orbital fat pad prolapsus and deepening of the lid sulcus from topical bimatoprost therapy: 2 case reports and review of the literature.
Mon, 02 Aug 2010 09:39:09 +0100 | Cutaneous and Ocular Toxicology
Conclusion: Clinicians and patients should be aware of these possible effects of topical bimatoprost therapy. These adverse effects may not be completely reversible after discontinuation of the medication.
PMID: 20670089 [PubMed - as supplied by publisher] (Source: Cutaneous and Ocular Toxicology)
Lipodermatosclerosis
Tue, 27 Jul 2010 23:00:00 +0100 | Dermatologic Therapy
The most commonly recognized form of lipodermatosclerosis (LDS), chronic LDS presents with induration and hyperpigmentation of the skin involving the one or both of the lower legs in a characteristic "inverted champagne bottle" appearance. Associated with venous insufficiency, LDS is most common in middle aged women. In addition to chronic LDS, an acute form may also occur and is often misdiagnosed as cellulitis, inflammatory morphea, or erythema nodosum. The "acute" refers to the symptoms present that are exquisite pain. Treatment of LDS is based on the clinical presentation with compression therapy as the mainstay of treatment if tolerated. For acute LDS, patients often cannot tolerate compression therapy due to pain. We advise the use of fibrinolytic therapy, if available, until the pat...