Andropause | Shim Clinic, Singapore

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Summary

Andropause | Shim Clinic, Singapore: Andropause test, treatment by Testosterone Replacement Therapy (TRT) with Nebido® injection, Andriol® oral capsules, or AndroGel® topical therapy

Description

• Hypogonadism
• Testosterone Deficiency Syndrome (TDS)
• Andropause
• Testosterone Replacement Therapy (TRT)

Table 1. Questions Used as Part of the Saint Louis University ADAM Questionnaire

1. Do you have a decrease in libido (sex drive)?
2. Do you have a lack of energy?
3. Do you have a decrease in strength and/or endurance?
4. Have you lost height?
5. Have you noticed a decreased "enjoyment of life"?
6. Are you sad and/or grumpy?
7. Are your erections less strong?
8. Have you noted a recent deterioration in your ability to play sports?
9. Are you falling asleep after dinner?
10. Has there been a recent deterioration in your work performance?

Reference

Morley JE, Charlton E, Patrick P, Kaiser FE, Cadeau P, McCready D, Perry HM 3rd. Validation of a Screening Questionnaire for Androgen Deficiency in Aging Males Metabolism. 2000 Sep;49(9):1239-42.

Hypogonadism in the male refers to the decrease in the functional activity of the male gonads (testis), resulting in a testosterone level falling below the normal range for a given age.

• Primary hypogonadism, or hypergonadotropic hypogonadism (high LH and/or FSH), or primary testicular failure. Eg: Klinefelters syndrome.
• Secondary hypogonadism, or hypogonadotropic hypogonadism (low LH and/or FSH), due to a defect in the hypothalamus or the pituitary.

Testosterone deficiency syndrome (TDS) refers to the clinical signs and symptoms that result from an abnormally low testosterone level, caused by hypogonadism.

Testosterone test and testosterone replacement therapy (TRT)

• Testosterone injection (Nebido®)
• Testosterone gel (AndroGel®)
• Andriol® oral capsules

Men's health issues:

• Hair loss
• Erectile dysfunction (ED)
• Premature ejaculation (PE)
• Andropause
• Testosterone deficiency syndrome (TDS)
• Testosterone replacement therapy (TRT)
• STD (Sexually transmitted disease)

• Andropause - Wikipedia, the free encyclopedia
• Andropause: Definition from Answers.com
• Andropause - definition of Andropause in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia.

Blunted Blood Pressure Response and Elevated Plasma Adiponectin Levels in Female Sprague Dawley Rats.
Thu, 19 Jan 2012 05:00:00 +0100 | American Journal of Hypertension
ConclusionsElevated plasma adiponectin levels, perhaps due to lack of suppression by testosterone, are associated with a blunting of BP response in female compared to male SD rats.American Journal of Hypertension 2012; doi:10.1038/ajh.2011.260. PMID: 22258332 [PubMed - as supplied by publisher] (Source: American Journal of Hypertension)

[Penile cystic lesion after intramuscular testosterone injection.]
Wed, 16 Nov 2011 05:00:00 +0100 | Anales de Pediatria
Authors: Sanz-Motilva V, Aransay-Brantot A, Pérez-Hurtado B, Martorell-Calatayud A PMID: 22098787 [PubMed - as supplied by publisher] (Source: Anales de Pediatria)

Doctors concerned over 'Low-T' treatments
Fri, 07 Oct 2011 18:49:24 +0100 | Health News - UPI.com
FORT LAUDERDALE, Fla., Oct. 7 (UPI) -- Doctors are urging caution as middle-age men seeking to restore their energy and sex drive are flocking to South Florida clinics for testosterone injections. (Source: Health News - UPI.com)

testosterone - intramuscular, Delatestryl, Everone, Tesamone
Wed, 21 Sep 2011 07:00:00 +0100 | MedicineNet Kids Health General
Title: testosterone - intramuscular, Delatestryl, Everone, TesamoneCategory: MedicationsCreated: 3/2/2005Last Editorial Review: 9/21/2011 (Source: MedicineNet Kids Health General)

Elevated testosterone during meiotic segregation stimulates laying hens to produce more sons than daughters.
Fri, 02 Sep 2011 04:00:00 +0100 | General and Comparative Endocrinology
Authors: Pinson SE, Wilson JL, Navara KJ Abstract Biases in avian sex ratios have been documented in relation to a variety of social and environmental conditions. Previous studies suggest that treatment with hormones can stimulate females to manipulate offspring sex, and that this effect occurs before ovulation. For example, acute and chronic treatments with testosterone stimulated significant skews towards male offspring. Hormones may act by influencing which sex chromosome is donated by the heterogametic female bird into the oocyte. However, it is difficult to pinpoint when effects of testosterone on offspring sex occurred in previous experiments because testosterone treatments were given either chronically over the entire period of follicular development or many hours before the...

Late-onset Boucher-Neuhauser Syndrome (late BNS) associated with white-matter changes: a report of two cases and review of literature
Wed, 06 Jul 2011 23:00:00 +0100 | Journal of Neurology, Neurosurgery and Psychiatry
Boucher–Neuhäuser syndrome (BNS) is rare autosomal recessive disease, characterised by cerebellar ataxia, hypogonadotropic hypogonadism and chorio-retinal degeneration. The authors report a family (brother, 22 years and sister 24 years) with late-onset BNS (>10 years). They had subnormal intelligence; the cerebellar ataxia was progressive over 2 years with early functional dependence. Puberty was attained in a brother with testosterone injections, while the girl had primary amenorrhoea. There were no associated visual complaints. They both had diffuse periventricular white-matter hyperintensities in cerebral cortex and diffuse cerebellar atrophy in the MRI. (Source: Journal of Neurology, Neurosurgery and Psychiatry)

Intestinal transplantation: current status and future directions
Fri, 20 May 2011 16:31:03 +0100 | Journal of Gastroenterology and Hepatology
AbstractThree decades after the first intestinal transplant was performed in humans, this life�saving procedure has come of age and now offers hope of long�term survival in a small group of patients with life�threatening complications of intestinal failure and parenteral nutrition. Success rates have greatly improved, largely through advances in immunosuppression protocols, improved surgical technique and post�operative care, and accumulated experience. Management of the intestinal transplant recipient entails careful surveillance, prevention, and treatment of rejection and infection, as well as optimisation of feeding and nutrition. With this approach, survival and quality of life are demonstrably improved, such that intestinal transplantation is now an established and accepted pr...

Effects of testosterone on spatial learning and memory in adult male rats.
Wed, 02 Feb 2011 00:00:00 +0100 | Hormones and Behavior
Authors: Spritzer MD, Daviau ED, Coneeny MK, Engelman SM, Prince WT, Rodriguez-Wisdom KN A male advantage over females for spatial tasks has been well documented in both humans and rodents, but it remains unclear how the activational effects of testosterone influence spatial ability in males. In a series of experiments, we tested how injections of testosterone influenced the spatial working and reference memory of castrated male rats. In the eight-arm radial maze, testosterone injections (0.500mg/rat) reduced the number of working memory errors during the early blocks of testing but had no effect on the number of reference memory errors relative to the castrated control group. In a reference memory version of the Morris water maze, injections of a wide range of testosterone doses (0.06...

DEPO-TESTOSTERONE (Testosterone Cypionate) Injection, Solution [Physicians Total Care, Inc.]
Fri, 21 Jan 2011 05:00:00 +0100 | DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST)
Updated Date: Jan 21, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))